Comparative evaluation of antidiabetic activity of some marketed polyherbal formulations in alloxan induced diabetic rats
نویسندگان
چکیده
A comparison was made between the antidiabetic activities of five different marketed polyherbal formulations in alloxan induced diabetic rats. Serum glucose and other biochemical parameters i.e. total protein, triglyceride and cholesterol were determined at the dose 800 mg/kg body weight, p.o. for 30 days. There is a significant increase in serum glucose (p<0.001) and improvement in the other biochemical parameters with treatment of polyherbal formulations which altered in diabetic rats as compared to the standard drug.
منابع مشابه
Evaluation of Antidiabetic Activity of a Polyherbal Formulation in Alloxan Induced Diabetic Rats
Objective of the study was to assess the antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats. Methods: The antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats was assessed using Alloxan βcytotoxin induced chemical diabetes in a wide variety of wister albino rats. Result: The polyherbal formulation contain the following plants leaves ...
متن کاملAntidiabetic Activity of Polyherbal Extract on Alloxan Induced Diabetic Rats
Polyherbal extract which consists of ethanolic extract of MadhucaLatifolia, AristolochiaBracteata, AristolochiaIndica was investigated for its possible antidiabetic effect in alloxan-induced diabetic rats and to assess the synergistic activity of three plants. The animals were grouped into four six animals each. The first group received normal saline solution(0.9% sodium chloride), which was us...
متن کاملAntidiabetic Effect of Kernals of Balanites roxburghii in Normal and Alloxan-induced Diabetic Rats
The antidiabetic activity of Balanites roxburghii was carried out in normal and alloxan-induced diabetic rats. Oral administration of methanolic extract of kernals (0.1 and 0.3g/kg body weight) significantly lowered the blood glucose levels. The activity can be attributed to reducing the intestinal absorption of glucose. The activity reported was dose-dependent.
متن کاملStudy of the antidiabetic activity of Punica granatum L. fruits aqueous extract on the Alloxan-diabetic Wistar rats
Pancreatic β-cells dysfunction and impairment of insulin action usually leads to hyperglycemia. Punica granatum L. is a well-known traditional herbal remedy in Iran due to its positive effects on ameliorating blood glucose homeostasis. In this study, we aimed to investigate and compare the pomegranate fruits aqueous extract (PE) on glucose and lipid metabolisms in normal and Alloxan-induced dia...
متن کاملAntidiabetic activity of a polyherbal formulation (DRF/AY/5001).
The herbal formulation, DRF/AY/5001, elicits hypoglycemic/antidiabetic effects in both normal and experimentally induced hyperglycemic (epinephrine and alloxan) rats. Further, herbal formulation treatment can significantly alter the pattern of glucose tolerance in normal and diabetic rats. It is possible that the herbal formulation may act through both, pancreatic and extra-pancreatic mechanism...
متن کامل